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Periodontal Disease
Periodontal disease is an infection of the tissues that support your teeth. Your gum tissue is not attached to the teeth as high as it may seem. There is a very shallow v-shaped crevice called a sulcus between the tooth and gums. Periodontal diseases attack just below the gum line in the sulcus, where they cause the attachment of the tooth and its supporting tissues to break down. As the tissues are damaged, the sulcus develops into a pocket: generally, the more severe the disease, the greater the depth of the pocket.
Periodontal diseases are classified according to the severity of the disease. The two major stages are gingivitis and periodontitis. Gingivitis is a milder and reversible form of periodontal disease that only affects the gums. Gingivitis may lead to more serious, destructive forms of periodontal disease called periodontitis.
Some factors increase the risk of developing periodontal disease:
- Tobacco smoking or chewing
- Systemic diseases such as diabetes
- Some types of medication such as steroids, some types of anti-epilepsy drugs, cancer therapy drugs, some calcium channel blockers and oral contraceptives
- Bridges that no longer fit properly
- Crooked teeth
- Fillings that have become defective
- Pregnancy or use of oral contraceptives
Several warning signs that can signal a problem:
- Gums that bleed easily
- Red, swollen, tender gums
- Gums that have pulled away from the teeth
- Persistent bad breath or bad taste
- Permanent teeth that are loose or separating
- Any change in the way your teeth fit together when you bite
- Any change in the fit of partial dentures
It is possible to have periodontal disease and have no warning signs. That is one reason why regular dental checkups and periodontal examinations are very important. Treatment methods depend upon the type of disease and how far the condition has progressed. Good oral hygiene at home is essential to help keep periodontal disease from becoming more serious or recurring. You don't have to lose teeth to periodontal disease. Brush, clean between your teeth, eat a balanced diet, and schedule regular dental visits for a lifetime of healthy smiles.

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Normal , healthy gums
Healthy gums and bone anchor teeth firmly in place. |
Periodontitis
Unremoved, plaque hardens into calculus (tartar). As plaque
and calculus continue
to build up, the gums
begin to recede (pull away) from the teeth,
and pockets form
between the teeth
and gums. |
Advanced periodontitis
The gums recede farther, destroying more bone and the periodontal ligament. Teeth — even healthy teeth — may become loose and need to be extracted. |
ARESTIN®
What is ARESTIN® (minocycline HCl) 1 mg Microspheres?
ARESTIN® is an effective antibiotic treatment that comes in powder form. This powder is placed inside infected periodontal pockets just after the dental professional finishes the scaling and root planing (SRP) procedure.
How does ARESTIN® work?
ARESTIN® powder contains "Microspheres," which are tiny, bead-like particles that are smaller than grains of sand and are not visible to the eye. The Microspheres are filled with the antibiotic minocycline, and they release the drug over time into the infected periodontal pocket, killing bacteria that live there.

ARESTIN® is proven in clinical studies
ARESTIN® Microspheres continue to fight the infection for up to 21 days after SRP. In clinical studies, ARESTIN® has been proven to be more effective than using SRP alone. ARESTIN® also significantly reduced the size of periodontal pockets compared to SRP alone.
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